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WIRF is one of Australia's leading organisations that is dedicated to improving the health of women and infants.

Shaofu Li

Shaofu Li

WIRF Laboratory Manager
  • Dr Shaofu Li was appointed as WIRF’s Laboratory Manager in 2004.

    He is a Research Scientist and Laboratory Manager at The University of Western Australia (UWA) School of Women’s and Infants’ Health based at King Edward Memorial Hospital.

    He is a fetal and maternal biophysics, biochemistry, molecular physiologist who did his PhD at UWA focusing on the fetal hypothalamic-pituitary adrenal axis and the effects of stress hormones during pregnancy on fetal development.
     
  • Dr Shaofu Li is a fetal and maternal biophysics, biochemistry, molecular physiologist who did his PhD at The University of Western Australia focusing on the fetal hypothalamic-pituitary adrenal axis and the effects of stress hormones during pregnancy on fetal development.

    Dr Shaofu Li studies the effects of prenatal steroid administration on the developing fetal hypothalamic-pituitary-adrenal function with the focus to the effects and mechanisms of prenatal glucocorticoids exposure on hypothalamic-pituitary-adrenal responses in fetus sheep and adult sheep. 

    Dr Shaofu Li focus also includes the prevention of pre-term birth in humans. 
     
    • Study the rate of preterm birth in China, the effects of migration on that rate, and the potential role of sex during pregnancy in causing early birth.
    • Study the potential role of a structured exercise program on preventing gestational (pregnancy) diabetes.
    • Bachelor of Science, Beijing Education Institute and Peking University, 1984.
    • Doctor of Philosophy, The University of Western Australia, 2013.
    • Best Oral Presentation Award at 2nd Asia Pacific Congress in Maternal Fetal Medicine, 2006
    • Travel award of 2nd Australia China Biomedical Research Conference, 2009
    • The University of Western Australia Research Collaboration Awards, 2011
    • Annual safety award of The University of Western Australia, 2013
    1. Li Shaofu, Moss J. M. Timothy, Nitsos Ilias, Matthews G. Stephen, Challis R. G. John, Newnham P. John and Sloboda M. Deborah. The impact of maternal synthetic glucocorticoid administration in late pregnancy on fetal and early neonatal hypothalamic-pituitary-adrenal axis regulatory genes is dependent upon dose and gestational age at exposure. J DOHaD (2013) 4: 77-89.
    2. Li Shaofu, Nitsos Ilias, Polglase R. Graeme, Newnham P. John, Challis R. G. John, and Moss J. M. Timothy. Effects of tail docking and castration on stress responses in lambs and the influence of prenatal glucocorticoid treatment. Reprod Fert Develop (2013) 25: 1020–1025.
    3. Li Shaofu, Sloboda M. Deborah, Moss J. M. Timothy, Nitsos Ilias, Polglase R. Graeme, Doherty A. Dorota, Newnham P. John, Challis R. G. John and Braun Thorsten. Effects of glucocorticoid treatment given in early or late gestation on growth and development in sheep. J DOHaD (2013) 4: 146-156.
    4. Payne MS, Feng Z, Li Shaofu, Doherty DA, Xu B, Li J, Liu L, Keelan JA, Zhou YH, Dickinson JE, Hu Y, Newnham JP Second trimester amniotic fluid cytokine concentrations, Ureaplasma sp. colonisation status and sexual activity as predictors of preterm birth in Chinese and Australian women. BMC Pregnancy Childbirth. (2014) 14:340-350.
    5. Ireland J Demelza, Nathan A Elizabeth, Li Shaofu, Charles K Adrian, Stinson F Lisa, Kemp W Matthew, Newnham P John and Keelan A Jeffrey Preclinical Evaluation of Drugs to Block Inflammation Driven Preterm Birth. Innate Immunity (2017) 23 (1): 20-33.
For over 40 years, WIRF has conducted and supported research to improve the health of women and infants.

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Contact details

Women and Infants Research Foundation
Carson House, King Edward Memorial Hospital
374 Bagot Road, Subiaco, WA 6008

Telephone: 08 6458 1437
Fax: 08 6458 1642
Email: info@wirf.com.au

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